Does mixing drinks, your age or quantity and type of alcohol make for a worse hangover?

by Katya Kowalski and Emily Clark   “That older adults experienced the least severe...
Created On: 22 September 2020   (Last updated: 09 October 2020)

by Katya Kowalski and Emily Clark

 

“That older adults experienced the least severe hangovers was unexpected”

Our recent research shows that the amount of alcohol you consume, the alcoholic drink type you consume, and whether you mix your alcoholic drink types may all contribute to the severity of hangover you experience.

Hangovers are the most commonly reported negative consequence of alcohol use and have a significant impact on daily functioning and mood. Therefore, understanding factors that influence hangover severity is vital in order to ensure individuals make more informed drinking decisions and minimise the negative effects of alcohol use.

Using the Drink Less App (Garnett et al., 2019), our study was one of the first to explicitly investigate the impact of a range of factors on hangover severity. App users would input their alcohol consumption and corresponding hangover severity ratings of clear-headedness, mood, productivity and sleep.

This study is novel through investigating hangover severity in real time, using Ecological Momentary Assessment (EMA; Shiffman et al., 2008). This design limits recall bias and maximises ecological validity by repeatedly sampling participants’ behaviours and feelings in real time. There is also a considerable amount of statistical power with a sample of over 5000 users.

We examined the association between amount and type of alcoholic beverage consumed and next-day hangover severity. We also examined the moderating influence of age and gender on the association between type of alcoholic beverage consumed and hangover severity.

Our findings indicated that mixing drink types was associated with poorer next-day productivity and clear-headedness. However, mixing drink types was not found to be associated with next-day mood or sleep.

There was an association between the type of alcoholic beverage consumed (beer, cider, wine, fortified wines, alcopops and spirits) and hangover severity. Wine was consistently associated with the highest hangover severity whereas beer, cider and spirits were associated with lower severity ratings.

An association was also found for the amount of alcohol consumed and subsequent hangover severity. The greater amount of alcohol consumed was found to result in an increase in hangover severity.

Increasing age was associated with decreased hangover severity. Age also moderated the relationship between alcohol consumption and hangover severity.

Gender was not associated with hangover severity. However, gender moderated the relationship between alcohol consumption and hangover severity. A moderated relationship means that a relationship between two variables (i.e. total units and hangover severity) depends on a third (i.e. gender or age).

 

“If people think that drinking wine gives them a terrible hangover, they are more likely to perceive their hangover as worse”

What do these findings mean?

Surprisingly, an association between mixing drink types and next-day hangover severity was found despite a lack of theory that could explain such effect. There are no current physiological explanations for why mixing drink types would increase hangover severity. Yet, the current study found that the number of drink types consumed was associated with poorer next-day productivity and clear-headedness. No association was found for mixing drink types and next-day mood and sleep which suggests that cognitive symptoms of a hangover may be more sensitive to the effects of alcohol. However, these findings may also be explained by other factors not controlled for in the study, such as the amount of sleep or food intake. Indeed, poor sleep has been shown to result in cognitive deficits, which may explain the increased impairments shown for productivity and clear-headedness (Jones & Harrison, 2001).

The association between drink type and hangover severity was surprising as previous research indicates the most meaningful association is between total alcohol consumption and hangover severity (Kochling et al., 2019; Scholey et al., 2019). Although, drink type appears to have a subjective impact on hangover severity (Rohsenow & Howland, 2009), which may explain these findings. An expectation to feel worse after certain drink types may lead to a more severe hangover subjectively. For example, if people think that drinking wine gives them a terrible hangover, they are more likely to perceive their hangover as worse. It is likely that expectations influence hangovers even when there is no pharmacological difference.

The association found between the amount of alcohol consumed and next-day hangover severity suggests that hangovers are “dose-dependent”. This means that the severity of hangover experiences is dependent on the amount of alcohol consumed. Specifically, our study suggests that the more alcohol you consume, the more severe hangover you experience as a consequence. This adds to the growing body of literature that implicates the role of alcohol dose on hangover severity (Chapman, 1970; Huntley et al., 2015).

That older adults experienced the least severe hangovers was unexpected as this counter’s biological explanations of an increased sensitivity to alcohol toxicity with age (Meier & Seitz, 2008). It is plausible that older adults have more protective factors which may have an impact on their hangover severity such as looking after their health to a greater extent (Lachman & Agrigoroaei, 2010).

Older adults may also be more tolerant to the effects of hangover due to being more accepting of pain and catastrophising to a smaller extent than young adults (Wetherell et al., 2016; Ruscheweyh et al., 2011; Czapla et al., 2015). As pain catastrophising worsens hangover outcomes (Royle et al., 2020), older individuals may perceive symptoms to be less severe.

Interestingly, sleep ratings were not associated with age. This is interesting as alcohol has a disruptive effect on sleep regulation (Thakkar et al., 2015). Sleep gets progressively worse with age (Kutner et al., 1994), making this finding surprising. However, sleep is a highly ambiguous term to score as it can be interpreted in various ways through either quality or quantity. So, it is possible the non-significant finding is due to a discrepancy in interpretation.

Age also moderated the relationship between alcohol consumption and hangover severity. This likely stems in older adults drinking less (Pabst et al., 2010) and ageing decreasing alcohol consumption due to being metabolised at a slower rate (Shaw et al., 2011).

Gender was not associated with hangover severity apart from ratings of productivity. Due to well-established gender differences in pain (Fillingim et al., 2009), it was expected that there would be differences in hangover severity. As women catastrophise their pain to a greater extent (Sullivan et al., 2000) and are more sensitive to ruminating (Nolen-Hoeksema, 1998), this may explain why they perceive themselves to be less productive during a hangover.

Nevertheless, gender moderated the relationship between alcohol consumption and hangover severity. This is supported by previous findings as women on average drink less than men and reach a higher blood-alcohol concentration level from the same amount of alcohol (Graham et al., 2002).

Despite these interesting findings, they must be interpreted with caution as the exact reasons for these relationships are yet to be confirmed.

 

What implications do these findings have?

This study has implications on developing a clearer picture for what factors influence hangover severity. Especially as there are a variety of popular anecdotal beliefs around what impacts hangover. By addressing these, we have exposed the subjectivity of hangover and the difficulty of disentangling the objective impact from expectations.

Furthermore, the role that individual differences play in hangover severity have significant implications on whether there are certain protective factors against alcohol use disorders, resulting in healthier drinking behaviours. For instance, how hangover severity influences subsequent drinking behaviour. Identifying modifiable drinking behaviours can help individuals to make more informed decisions regarding their alcohol use and consequently minimise the burden of alcohol use to society.

Investigating how objective hangover severity interacts with subjective severity is also of interest. This will help us determine and allow for a comparison between objective and subjective severity to determine whether here are discrepancies. This will highlight whether, and to what extent, expectations play a part in hangovers and how this influences mood as this is a highly subjective rather than objective feeling.

Katya Kowalski has recently completed her Health Psychology MSc at the University of Bath. She has a strong interest in addictive behaviours and psychopharmacology research.

Emily Clark is a recent MSc Health Psychology graduate with a keen interest in alcohol research.

References

Chapman, L. (1970). Experimental Induction of Hangover. Quarterly Journal Of Studies On Alcohol, Supplement, 31(S5), 67-86. doi: 10.15288/qjsas.1970.s5.067

Czapla, M., Simon, J.J., Friederich, H.C., Herpertz, S.C., Zimmermann, P., & Loeber, S. (2015). Is Binge Drinking in Young Adults Associated with an Alcohol-Specific Impairment of Response Inhibition? European Addiction Research, 21(2), 105-113. doi:10.1159/000367939

Fillingim, R.B., King, C.D., Ribeiro-Dasilva, M.C., Rahim-Williams, B., & Riley, J.L., 3rd. (2009). Sex, gender, and pain: a review of recent clinical and experimental findings. Journal of Pain, 10(5), 447-485. doi:10.1016/j.jpain.2008.12.001

Garnett, C., Crane, D., West, R., Brown, J., & Michie, S. (2019). The development of Drink Less: an alcohol reduction smartphone app for excessive drinkers. Translational Behavioural Medicine, 9(2), 296-307. doi10.1093/tbm.iby043

Graham, K., Wilsnack, R., Dawson, D., & Vogeltanz, N. (2002). Should alcohol consumption measures be adjusted for gender differences? Addiction, 93(8), 1137-1147. doi:10.1046/j.1360-04443.1998.93811372.x

Huntley, G., Treloar, H., Blanchard, A., Monti, P., Carey, K., Rohsenow, D., & Miranda, R. (2015). An event-level investigation of hangovers’ relationship to age and drinking. Experimental And Clinical Psychopharmacology, 23(5), 314-323. doi: 10.1037/pha0000037

Jones, K., & Harrison, Y. (2001). Frontal lobe function, sleep loss and fragmented sleep. Sleep Medicine Reviews, 5(6), 463-475. doi: 10.1053/smrv.2001.0203

Kochling, J., Geis, B., Wirth, S., & Hensel, K.O. (2019). Grape or grain but never the twain? A randomized controlled multiarm matched-triplet crossover trial of beer and wine. The American Journal of Clinical Nutrition, 109(2), 345-352. doi:10.1093/ajcn/nqy309

Kutner, N.G., Schechtman, K.B., Ory, M.G., Baker, D.I. & FICSIT Group. (1994). Older Adults’ Perceptions of their Health and Functioning in Relation to Sleep Disturbance, Falling, and Urinary Incontinence. Journal of the American Geriatrics Society, 42(7), 757-762. doi:10.1111/j.1532-5415.1994.tb065437.x

Lachman, M.E., & Agrigoroaei, S. (2010). Promoting Functional Health in Midlife and Old Age: Long-Term Protective Effects of Control Beliefs, Social Support, and Physical Exercise. PLOS One, 5(1), e13297. doi:10.1371/journal.pone.0013297

Meier, P., & Seitz, H.K. (2008). Age, Alcohol Metabolism and Liver Disease. Curr Opin Clin Nutr Metab Care, 11(1), 21-26. doi:10.1097/MCO.0b013e3282f30564

Nolen-Hoeksema, S. (1998). Ruminative coping with depression. In J. Heckhausen & C.S. Dweck (Eds.)., Motivation and self-regulation across the life span (p. 237-256). Cambridge University Press. doi:10.1017/CBO9780511527869.011

Pabst, A., Baumeister, S.E., & Kraus, L. (2010). Alcohol-Expectancy Dimensions and Alcohol Consumption at Different Ages in the General Population. Journal of Studies on Alcohol and Drugs, 71(1), 46-53. doi:10.15288/jsad.2010.71.46

Rohsenow, D.J., & Howland, J. (2009). The role of beverage congeners in hangover and other residual effects of alcohol intoxication: A review. Current Drug Abuse Reviews, 3(2), 76-79. doi:10.2174/1874473711003020076

Royle, S., Owen, L., Roberts, D., & Marrow, L. (2020). Pain Catastrophizing Predicts Alcohol Hangover Severity and Symptoms. Journal of Clinical Medicine, 9(1), 280.doi:10.3390/jcm9010280

Ruscheweyh, R., Nees, J., Marziniak, M., Evers, S., Flor, H., & Knecht, S. (2011). Pain Catastrophizing and Pain-Related Emotions: Influence of Age and Type of Pain. The Clinical Journal of Pain, 27(7), 578-586. doi:10.1097/AJP.0b013e31820fde1b

Scholey, A., Benson, S., Kaufman, J., Terpstra, C., Ayre, E., Verster, J.C., Allen, C., & Devilly, G.J. (2019). Effects of Alcohol Hangover on Cognitive Performance: Findings from a Field/Internet Mixed Methodology Study. Journal of Clinical Medicine, 8(4), 440. doi:10.3390/jcm8040440

Shaw, B.A., Krause, N., Liang, J., & McGeever, K. (2011). Age Differences in Long-Term Patterns of Change in Alcohol Consumption Among Aging Adults. Journal of Aging and Health, 23(2), 207-227. doi:10.1177/0898264319381276

Shiffman, S., Stone, A.A., & Hufford, M.R. (2008). Ecological momentary assessment. Annu Rev Clin Psychol, 4(1), 1-32. doi:10.1146/annurev.clinpsych.3.022806.091415

Sullivan, M.J.L., Tripp, D.A., & Santor, D. (2000). Gender Differences in Pain and Pain Behavior: The Role of Catastrophizing. Cognitive Therapy and Research, 24(1), 121-134.doi:10.1023/A:1005459110063

Thakkar, M.M., Rishi, S., & Sahota, P. (2015). Alcohol disrupts sleep homeostasis. Alcohol, 49(4), 299-310. doi:10.1016/j.alcohol.2014.07.019

Wetherell, J.L., Petkus, A.J., Alonso-Fernandez, M., Bower, E.S., Steiner, A.R.W., & Afari, N. (2016). Age moderates response to acceptance and commitment therapy vs. cognitive behavioural therapy for chronic pain. International Journal of Geriatric Psychiatry, 31(3), 302-308.doi:10.1002/gps.4330

 

The opinions expressed in this post reflect the views of the author(s) and do not necessarily represent the opinions or official positions of the SSA.

The SSA does not endorse nor guarantee the accuracy of the information in external sources or links and accepts no responsibility or liability for any consequences arising from the use of such information.

Categories
Research
Categories
Alcohol